On Sunday, the 1st XI hosted near neighbours Wavertree in the second round of the Ray Tyler Cup.
Skipper Paul Horton top scored with 80 with valuable contributions from Andy Hale (40) and James Stirling (26) as the hosts reached 232-9 off their 45 overs.
Wavertree were 7-2 but recovered to reach 190-8 in a rain affected game which ended with Sefton winning on a DLS decision by 18 runs after Wavertree had been set 209 from 37 overs.
The 1st XI will now play the winners of Old Xaverians and Parkfield Liscard in a semi final - date TBC.
Paul Horton hit 80 in the cup victory over Wavertree
The 2nd XI were also in action and travelled to Southport and Birkdale for a re-arranged league fixture following Trafalgar Road's recent use by Lancashire.
The hosts won the toss and batted first before declaring on 187-6 off 39 overs with Dave Kelly's 3-31 off 14 overs the pick of the figures.
Sefton's reply was based around the innings of Devadruv Malyavantham Chittaranjan, who hit 76 off 100 balls, and Navi Singh, who hit a 24 ball 46, including four fours and four sixes, as the visitors passed the target for the loss of seven wickets in the 34th over. They are now top of the league by one point from Ormskirk.
Rain spoiled Phil McLoughlin's Sunday XI's trip to New Brighton after the visitors had made 139-7. Phil led the way with 30 with Rajiv Bhardwaj scoring 22 before the heavens opened.
The Women's 1st XI were in action against Hightown Hurricanes in the Women's T20 League. Sefton reached 97-5 with Lauren Rutland hitting an unbeaten 32. Caitlin Summers took 2-13 but Hightown passed the total for the loss of four wickets in the 17th over.